A needle-free nasal immunization, using a combination of nanoemulsion and hepatitis B antigen, could be a safe and effective hepatitis B vaccine, and also provide an alternative booster method for existing vaccines according to Dr. James Baker Jr., The first human trial can begin within a year. The study is reported in the online journal PLoS One.
University of Michigan researchers said the new nanoemulsion eliminates three major problems associated with current vaccines -- the need for refrigeration, difficulty in maintaining needle and syringe sterility and the need for people to return for the three-shot regimen.
Although there are three effective vaccines available, hepatitis B infects 400 million people worldwide, many of them children in Africa, Asia and South America.
University of Michigan researchers said the new nanoemulsion eliminates three major problems associated with current vaccines -- the need for refrigeration, difficulty in maintaining needle and syringe sterility and the need for people to return for the three-shot regimen.
Although there are three effective vaccines available, hepatitis B infects 400 million people worldwide, many of them children in Africa, Asia and South America.
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